Effect of glucose-dependent insulinotropic polypeptide on whole-body glucose utilization in sheep
نویسندگان
چکیده
منابع مشابه
Glucose-Dependent Insulinotropic Polypeptide
OBJECTIVE To evaluate the glucose dependency of glucose-dependent insulinotropic polypeptide (GIP) effects on insulin and glucagon release in 10 healthy male subjects ([means ± SEM] aged 23 ± 1 years, BMI 23 ± 1 kg/m(2), and HbA(1c) 5.5 ± 0.1%). RESEARCH DESIGN AND METHODS Saline or physiological doses of GIP were administered intravenously (randomized and double blinded) during 90 min of ins...
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Glucose-dependent insulinotropic polypeptide (GIP) is a 42-amino acid peptide produced by K cells of the mammalian proximal small intestine and is a potent stimulant of insulin release in the presence of hyperglycemia. However, its relative physiological importance as a postprandial insulinotropic agent is unknown. Using LGIPR2 cells stably transfected with rat GIP receptor cDNA, GIP (1-42) sti...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 1998
ISSN: 0958-0670
DOI: 10.1113/expphysiol.1998.sp004159